From GersteinInfo
Data from "Consistent negative selection constraints at protein-coding sites across broad evolutionary time-scales" by Khurana et al
Omega (dN/dS) values for all coding sites in Gencodev3b computed from 12 whole-genome vertebrate alignments using PAML.
omega_values_for_all_codons
Omega values for sites identified as being under positive selection in humans relative to vertebrates (omega > 1 and probability (omega>1) > 0.5)
Codons_under_positive_selection
Allele frequencies of non-synonymous SNPs at sites that are identified as being under positive selection in humans relative to vertebrates and are polymorphic amongst humans
in 1000 Genomes Pilot 1 data
Pos_sel_SNP sites
Gap_scores for deletions from 1000 Genomes Pilot 1 data (1KG-DELs) computed from 28 whole-genome vertebrate alignments
1KG-gap_scores
Gap_scores for disease-causing deletions from HGMD (HGMD-DELs) computed from 28 whole-genome vertebrate alignments
HGMD-gap_scores
Structural conservation scores for non-synonymous SNPs from 1000 Genomes Pilot 1 data (1KG-SNPs)
1KG-str_cons
Structural conservation scores for disease-causing non-synonymous single nucleotide variants from HGMD (HGMD-SNVs)
HGMD-str_cons
