Hierarchy
From GersteinInfo
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by Nitin Bhardwaj, Philip M. Kim and Mark B. Gerstein
Please cite the above article if usage of the following date results in a publication.
Data:
The regulatory network for [/nfs/archive/html/proj/Hierarchy_Rewiring/Yeast_reg.txt Yeast] and [/nfs/archive/html/proj/Hierarchy_Rewiring/Ecoli_reg.txt E. coli]. The file is in a tab-delimited format with the regulator followed by the target in the same line. For E. coli, the last column also list the type of regulation: "+" for positive, "-" for negative and "+-" for dual regulation.
| Yeast | E. coli | |
|---|---|---|
| Number of regulatory interactions | 12873 | 3123 |
| Number of Regulators | 288 | 143 |
| Number of Targets | 4410 | 1420 |
| Number of Inter-Regulator interactions | 632 | 220 |
Assignment into hierarchies for Yeast and E. coli.
Changes in hierarchies:
Indirect Targets and Number of targets vs position in the hierarchy (in one of the four levels) for E. coli and Yeast.
Effects of Overexpression
