Prosnp
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(→Data from "Consistent negative selection constraints at protein-coding sites across broad evolutionary time-scales" by Khurana et al) |
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| - | ==Data from " | + | ==Data from "Comparing selective pressure at protein-coding sites across broad evolutionary time-scales" by Khurana et al== |
| - | Omega (dN/dS) values for all coding sites in Gencodev3b computed from | + | Omega (dN/dS) values for all coding sites in Gencodev3b computed from 12 whole-genome vertebrate alignments using PAML. |
| - | [http://archive.gersteinlab.org/prosnp/all_omega | + | [http://archive.gersteinlab.org/prosnp/all_omega omega_values_for_all_codons] |
Omega values for sites identified as being under positive selection in humans relative to vertebrates (omega > 1 and probability (omega>1) > 0.5) | Omega values for sites identified as being under positive selection in humans relative to vertebrates (omega > 1 and probability (omega>1) > 0.5) | ||
| - | [http://archive.gersteinlab.org/prosnp/omega_pos_sel | + | [http://archive.gersteinlab.org/prosnp/omega_pos_sel Codons_under_positive_selection] |
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| + | Allele frequencies of non-synonymous SNPs at sites that are identified as being under positive selection in humans relative to vertebrates and are polymorphic amongst humans | ||
| + | in 1000 Genomes Pilot 1 data | ||
| + | [http://archive.gersteinlab.org/prosnp/pos_sel_snps Pos_sel_SNP sites] | ||
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| + | Gap_scores for deletions from 1000 Genomes Pilot 1 data (1KG-DELs) computed from 28 whole-genome vertebrate alignments | ||
| + | [http://archive.gersteinlab.org/prosnp/gap_score_1kg 1KG-gap_scores] | ||
| + | |||
| + | Gap_scores for disease-causing deletions from HGMD (HGMD-DELs) computed from 28 whole-genome vertebrate alignments | ||
| + | [http://archive.gersteinlab.org/prosnp/gap_score_hgmd HGMD-gap_scores] | ||
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| + | Structural conservation scores for non-synonymous SNPs from 1000 Genomes Pilot 1 data (1KG-SNPs) | ||
| + | [http://archive.gersteinlab.org/prosnp/str_cons_1kg 1KG-str_cons_scores] | ||
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| + | Structural conservation scores for disease-causing non-synonymous single nucleotide variants from HGMD (HGMD-SNVs) | ||
| + | [http://archive.gersteinlab.org/prosnp/str_cons_hgmd HGMD-str_cons_scores] | ||
Latest revision as of 02:26, 7 August 2011
Data from "Comparing selective pressure at protein-coding sites across broad evolutionary time-scales" by Khurana et al
Omega (dN/dS) values for all coding sites in Gencodev3b computed from 12 whole-genome vertebrate alignments using PAML. omega_values_for_all_codons
Omega values for sites identified as being under positive selection in humans relative to vertebrates (omega > 1 and probability (omega>1) > 0.5) Codons_under_positive_selection
Allele frequencies of non-synonymous SNPs at sites that are identified as being under positive selection in humans relative to vertebrates and are polymorphic amongst humans in 1000 Genomes Pilot 1 data Pos_sel_SNP sites
Gap_scores for deletions from 1000 Genomes Pilot 1 data (1KG-DELs) computed from 28 whole-genome vertebrate alignments 1KG-gap_scores
Gap_scores for disease-causing deletions from HGMD (HGMD-DELs) computed from 28 whole-genome vertebrate alignments HGMD-gap_scores
Structural conservation scores for non-synonymous SNPs from 1000 Genomes Pilot 1 data (1KG-SNPs) 1KG-str_cons_scores
Structural conservation scores for disease-causing non-synonymous single nucleotide variants from HGMD (HGMD-SNVs) HGMD-str_cons_scores
